This reading list draws together resources that we think will be helpful if you are undertaking MAMS trials. It is not an exhaustive list but rather a recommended package of resources.

 

 

MAMS platform trials: motivation, strategic and practical issues

 

Video

Motivation for MAMS trials

Video

An introduction to MAMS designs

Video 

MAMS platform trials: statistical and designs issues 

Video

Workshop tutorial for MAMS trials (Analysis and issue of bias in the estimate of treatment effect in TAMS trials) 

Video

Novel designs for multi-arm clinical trials with survival outcomes with an application in ovarian cancer (foundational ref for group sequential design)

Paper (website)

Optimal multi-arm multi-stage (MAMS) platform randomized trials using Stata: Rationale, design, and implementation

Slides

Multi-arm Multi-stage (MAMS) Platform Randomized Clinical Trials

Book chapter (website)

MAMS platform trials: application to abdominal surgery (ROSSINI 2)

 

Video 

MAMS platform protocols: Patient engagement in STAMPEDE and beyond

 

Slides

 

 

 

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